Mechanistic Modeling Approach to Prediction & Analysis of Clinical Trial Results in Neurodegeneration
Time: 10:35 am
day: Day One
- Quantitative system pharmacology (QSP) modeling of clinical trials facilitates interpretation of information provided by biomarkers.
- QSP methods allows for investigation of interaction between pathological mechanisms, biomarkers and treatment: example for aducanumab clinical trial.
- Combinatorial therapy efficacy on endpoints, intrinsic mechanisms and
biomarkers can be potentially predicted by QSP