Danielle Graham

Danielle Graham

Company: Biogen

Job title: Senior Director, Discovery & Clinical Biomarkers


Dr. Danielle Graham received her Ph.D. in Neuroscience from Baylor University in 2002.  She completed her postdoctoral research at the University of Texas Southwestern Medical Center in Dallas, TX working with Dr. David Self and Dr. Eric Nestler.  Dr. Graham moved to Boston MA in 2007 to join the AD group at Merck Research Labs (MRL).  In 2009, Dr. Graham moved to EMD Serono Research Institute, where as a group leader she was responsible for leading a team of scientists in the identification and characterization of novel therapeutics and translational endpoints for CNS Disease.  In 2014, Dr. Graham moved to Biogen in Cambridge MA and is currently Sr Director, Discovery and Clinical Biomarkers leading a brilliant team of scientists who are focused on the development of novel fluid biomarkers in Neurodegenerative Disease including AD.  Two key objectives of her team are to develop novel biomarkers that help de-risk therapeutic development in early clinical studies as well as advance disease relevant biomarkers that provide an early indicator of clinical efficacy.


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Employing Biomarkers to De-risk Therapeutic Development in AD 11:20 am

Aiding the developing of novel therapeutics in clinical trials by inclusion of fluid and imaging biomarkers Exploring AD case study evidence to evaluate the importance of patient selection tools, target engagement/ pharmacodynamic measures and biomarkers of disease progressionRead more

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